MicroRNA Biogenesis: Drosha Can't Cut It without a Partner

نویسندگان

  • Yukihide Tomari
  • Phillip D. Zamore
چکیده

The ribonuclease Drosha requires a dedicated double-stranded RNA binding protein to convert long, nuclear primary microRNA transcripts into shorter pre-microRNA stem-loops, the cytoplasmic precursors from which mature microRNAs are ultimately excised.

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عنوان ژورنال:
  • Current Biology

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2005